Which king and queen of Spain are known for funding Columbus' voyages?

Ferdinand and Isabella, the Catholic Monarchs of Spain, are renowned for their role in sponsoring Christopher Columbus's expeditions across the Atlantic Ocean. Their decision to fund Columbus in 1492 was pivotal in initiating European exploration of the Americas, marking a significant moment in history. Ferdinand and Isabella sought to expand Spain's influence and territory, as well as to spread Christianity. By providing Columbus with ships and resources, they empowered him to embark on a journey that ultimately led to the European discovery of the New World.

The other pairs mentioned do not have historical ties to supporting Columbus's voyages. Charles and Catherine and Philip and Mary, for example, were associated with later periods and monarchs in Spanish history, while Louis and Anne are not linked to Spanish royalty during the Age of Exploration, making Ferdinand and Isabella the clear choice in this context.